Absolutely! Conditional formatting is a powerful tool in Excel that can be used to format cells based on various conditions, including dates and times. Here's how you can achieve this:

1. Select the cells you want to format: Choose the range of cells containing the dates or times you want to apply conditional formatting to.

2. Go to Conditional Formatting: Navigate to the "Home" tab on the Excel ribbon. In the "Styles" group, click the dropdown arrow under "Conditional Formatting."

3. Highlight Cell Rules or Use a Formula: You have two main approaches:
- Highlight Cell Rules: This offers pre-defined options for formatting based on dates. Choose "Highlight Cells Rules" and then select options like "Dates Occurring In..." (e.g., Today, This Week, Next Month) or "Older Than..."/"Younger Than..." a specific date.
- Use a Formula: This allows for more flexibility. Click "New Rule" and choose "Format values where this formula is true." Enter a formula using Excel date and time functions like TODAY(), WEEKDAY(), YEAR(), HOUR(), MINUTE(), etc. to define your formatting condition.

4. Set Formatting: Once you've chosen your approach, define the formatting you want to apply when the condition is met. This can include changing cell fill color, font style, borders, and more. Click the "Format" button and choose your desired options.

5. Click OK: After setting up the rule and formatting, click "OK" to apply the conditional formatting to your selected cells.

By leveraging conditional formatting with dates and times, you can easily highlight upcoming deadlines, overdue tasks, specific date ranges, or any other time-based criteria you want to visualize within your spreadsheet.