Absolutely! You can combine multiple conditional formatting rules for a single cell in Excel. There are two main ways to achieve this:

1. Applying Multiple Rules Sequentially:

- You can add multiple conditional formatting rules one after the other. Excel will evaluate the rules in the order they are listed. The first rule that evaluates to TRUE will determine the formatting applied to the cell.
- Important: When using this method, make sure to prioritize your rules. Place the most specific rule (the one that should be applied most often) at the top of the list and the more general rules below. For example, a rule highlighting negative values should be above a rule highlighting all non-blank cells.
- To manage the order and edit existing rules, use the Conditional Formatting Rules Manager found under the "Conditional Formatting" dropdown on the Home tab.

2. Using the AND Function in a Formula:

- You can create a single conditional formatting rule with a formula that combines multiple conditions using the AND function. This allows for more complex formatting logic based on meeting all the specified criteria.
- For example, you could create a rule that highlights a cell red if the value is greater than 10 AND the text contains the word "urgent." The formula for this rule would be: `=AND(A1>10,SEARCH("urgent",A1,1)>0)`.

By combining these techniques, you can create powerful conditional formatting that tailors the cell's appearance based on various conditions, providing a clear and informative view of your data.